Welcome to the Yellow Card reporting site
Anyone can report an issue with a medicine, vaccine, medical device (including software, apps and artificial intelligence), blood product or e-cigarette to the Yellow Card scheme.
The Yellow Card scheme is run by the Medicines and Healthcare products Regulatory Agency (MHRA), which safeguards medical products quality and efficacy in the United Kingdom.
Reporting makes a big difference
Your Yellow Card report plays a key part in keeping others safe. Your experience can ensure that all healthcare products can continue their positive impact on peoples’ lives, by helping the MHRA identify new safety issues as early as possible.
You can find examples of where reporting to the Yellow Card scheme has made a difference in our case studies. You can also view information on what is being reported.
Worried about your health?
Speak to your doctor, pharmacist or to call NHS 111 if you are worried about your health. If you’re deaf and want to use the phone service, you can use the NHS 111 British Sign Language service available in your country.
We are unable to provide you with medical advice.
Always read the patient information leaflet, or instructions supplied with your medicine or medical device. It lists the known side effects or problems and advises you on what to do.
Safety updates
See all safety updates#MedSafetyWeek campaign: 3-9 November 2025
Our tenth annual #MedSafetyWeek campaign runs from 3 to 9 November 2025. The theme is ‘we can all help make medicines safer’.
See our #MedSafetyWeek page on how to get involved and help us raise awareness. Get involved and support by reposting, liking and sharing our posts using #MHRAYellowCard and #MedSafetyWeek on social media. Every Yellow Card report counts.
Patient safety essay competition 2025
Calling the Next Generation of Doctors: Explore How Genetics Can Improve Prescribing and Patient Safety
We are inviting medical students and foundation doctors across the United Kingdom to share their insights on the vital role of genetics in enhancing the efficacy and safety of medicines for patients. This competition offers a unique platform for future clinicians to influence national thinking on medicine safety and pharmacovigilance. See here for more information.